Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304303 | 1.00 | MAPT (0.41) | MAPTBTN3A1BACE1CYP2C19CYP3A4 | |
| SCHEMBL5820033 | 0.88 | IDO1 (0.35) | MAPTBACE1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL1751842 | 0.88 | IDO1 (0.35) | MAPTBACE1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL9304192 | 0.81 | BTN3A1 (0.33) | MAPTBTN3A1BACE1CYP2C19CYP3A4 | |
| SCHEMBL7530664 | 0.80 | CA1 (0.37) | MAPTSLC1A1KMT2ATSHRELANE | |
| SCHEMBL9305298 | 0.78 | MAPT (0.38) | MAPTBTN3A1BACE1CYP2C19CYP3A4 | |
| SCHEMBL9305302 | 0.78 | MAPT (0.38) | MAPTBTN3A1BACE1CYP2C19CYP3A4 | |
| SCHEMBL1751064 | 0.77 | — | — | |
| SCHEMBL1751884 | 0.76 | IDO1 (0.35) | MAPTCYP2C19CYP3A4CYP2C9TSHR | |
| SCHEMBL1751885 | 0.76 | IDO1 (0.35) | MAPTCYP2C19CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332807-A | Process of producing 8A- and 9A-azalide antibiotics | MERCK & CO., INC. (US) | 1994-07-26 | — | — | US | disclosed |