SCHEMBL753096

SCHEMBL753096

Clc1cccccccs1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
LMNA P02545 2/20 0.35
NOS1 P29475 1/20 0.34
CYP1A2 P05177 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGDS O60760 1/20 0.33
DAO P14920 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FBP1 P09467 1/20 0.32
PDPK1 O15530 1/20 0.31
CYP2A6 P11509 2/20 0.31
BCAT2 O15382 1/20 0.30
ALOX15 P16050 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423529 1.00 TSHR (0.40) TSHRLMNANOS1CYP1A2ALDH1A1
SCHEMBL7073829 0.88
SCHEMBL29054 0.88
SCHEMBL3276946 0.85
Hydrogen Sulfide SCHEMBL29248841 0.85
SCHEMBL497681 0.85
SCHEMBL6830319 0.85
SCHEMBL2975655 0.85
Ammonia Solution, Strong SCHEMBL28811677 0.85
SCHEMBL8666743 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3062458-A None JP disclosed
EP-3593786-B1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORP (JP) 2022-05-18 EP disclosed
US-11273104-B2 Photocurable composition and dental restoration filling material TOKUYAMA DENTAL CORPORATION (JP) 2022-03-15 US disclosed
EP-3427716-B1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2021-11-24 EP disclosed
CN-108697586-B Photopolymerization initiator and photocurable composition 株式会社德山齿科 2021-07-06 CN disclosed
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2021-04-01 US disclosed
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL TOKUYAMA DENTAL CORPORATION (JP) 2020-03-05 US disclosed
CN-110249007-A Thiosulfonic acid is synthesized with the oxidative coupling step that the periodic acid class of aniline mediates by thiosulfonic acid 维斯塔实验室有限公司 2019-09-17 CN disclosed
CN-110092764-A Diaminophenothiazine compound includes the chemical synthesis process of methyl sulfonium chloride (MTC) 维斯塔实验室有限公司 2019-08-06 CN disclosed
CN-109789148-A Administration and dosage of diaminophenothiazines 维斯塔实验室有限公司 2019-05-21 CN disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
EP-0738928-B1 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORP (JP) 2001-06-20 EP disclosed
WO-1999066307-A1 APPARATUS AND METHODS FOR DETERMINING THE TIME OF DEATH OF AN ORGANISM BIOMAX TECHNOLOGIES, INC. (CA) 1999-12-23 WO disclosed
WO-1998052017-A1 APPARATUS AND METHODS FOR DETERMINING THE TIME OF DEATH OF AN ORGANISM BIOMAX TECHNOLOGIES, INC. (CA) 1998-11-19 WO disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed
US-5500760-A Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1996-03-19 US disclosed
EP-0531143-A2 Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1993-03-10 EP disclosed
JP-H0362458-A LITHIUM BATTERY MITSUBISHI ELECTRIC CORP 1991-03-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273104-B2 Photocurable composition and dental restoration filling material H1-0, REV1, RER1 TSHR 3666/4885LMNA 266/4885NOS1 31/4885
US-20210095055-A1 PHOTOPOLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION INO80C, JAK2, PCNA TSHR 1296/4885LMNA 1349/4885NOS1 1946/4885
US-20200069534-A1 PHOTOCURABLE COMPOSITION AND DENTAL RESTORATION FILLING MATERIAL REV1, H1-0, RAD51 TSHR 3713/4885LMNA 271/4885NOS1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.