Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527308 | 1.00 | EGFR (0.46) | EGFRSMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL17974969 | 0.81 | TAAR1 (0.48) | EGFRSMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL9806913 | 0.79 | SLC6A2 (0.47) | EGFRSMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL9810146 | 0.75 | SLC6A2 (0.50) | EGFRSMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL11043392 | 0.73 | SLC6A2 (0.48) | EGFRSMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL28101998 | 0.72 | SLC6A2 (0.56) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL28101982 | 0.72 | SLC6A2 (0.56) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL3361395 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| Acetic Acid SCHEMBL1551090 | 0.71 | HIF1A (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL4359977 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049350-A1 | Process for preparing thrombin receptor antagonist building blocks | FU XIAOYONG (US) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049350-A1 | Process for preparing thrombin receptor antagonist building blocks | F2R, TFPI, TBXA2R | EGFR 119/4885SMN1; SMN2 4133/4885HIF1A 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.