Acetic Acid

Acetic Acid

SCHEMBL1551090

CC(=O)O.CC(C)(O)Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SLC6A2 P23975 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
FDPS P14324 1/20 0.48
CYP2C19 P33261 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP1A2 P05177 2/20 0.48
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 3/20 0.47
LMNA P02545 3/20 0.47
CYP2D6 P10635 2/20 0.47
TRPA1 O75762 1/20 0.46
MEN1 O00255 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
SCN1A P35498 1/20 0.45
KMT2A Q03164 1/20 0.45
SCN2A Q99250 1/20 0.45
SCN3A Q9NY46 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21353 0.91 SLC6A2 (0.58) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
SCHEMBL28101998 0.89 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
Bromide SCHEMBL28597373 0.89 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
SCHEMBL28366661 0.89 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
SCHEMBL28101982 0.89 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
SCHEMBL28366193 0.89 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
Acetophenone SCHEMBL27816554 0.88 LMNA (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
Acetic Acid SCHEMBL30303159 0.88 CYP2C19 (0.44) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
SCHEMBL6565911 0.86 TRPA1 (0.50) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS
Benzophenone SCHEMBL27920919 0.86 ALDH1A1 (0.54) HIF1ASMN1; SMN2SLC6A2TAAR1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4381037-B1 METHOD UNILEVER IP HOLDINGS B V (NL) 2025-04-23 EP claimed
US-20250101339-A1 METHOD CONOPCO, INC. (US) 2025-03-27 US claimed
EP-4381037-A1 METHOD Unilever IP Holdings B.V. (NL) 2024-06-12 EP claimed
CN-117795044-A Method 联合利华知识产权控股有限公司 2024-03-29 CN claimed
CN-117147721-A Method for distinguishing fermented soybeans from fermented soybeans 中南林业科技大学 2023-12-01 CN claimed
WO-2023012098-A1 METHOD UNILEVER IP HOLDINGS B.V. (NL) 2023-02-09 WO claimed
WO-2023012093-A1 METHOD UNILEVER IP HOLDINGS B.V. (NL) 2023-02-09 WO claimed
CN-115517398-A Green plum green tea electronic atomized liquid and preparation method thereof 深圳市真味生物科技有限公司 2022-12-27 CN claimed
CN-115353932-A Essence composition for controlling saponification speed, application thereof and cold soap 江门市和馨香精技术有限公司 2022-11-18 CN claimed
EP-3709804-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB Applied Technologies, LLC (US) 2020-09-23 EP claimed
CN-108300608-B Long-acting fragrance-retaining composition, perfume and laundry detergent 广州爱伯馨香料有限公司 2020-07-24 CN claimed
US-20190133127-A1 Pesticidal Compositions and Related Methods CJB APPLIED TECHNOLOGIES, LLC 2019-05-09 US claimed
US-8277824-B2 Solubilization of cyclohexane-based carboxamide derivatives for use as sensates in consumer products THE PROCTER & GAMBLE COMPANY (US) 2012-10-02 US claimed
EP-2313070-A1 SOLUTION OF MENTHANE CARBOXAMIDES FOR USE IN CONSUMER PRODUCTS The Procter & Gamble Company (US) 2011-04-27 EP claimed
WO-2010019729-A1 SOLUTION OF MENTHANE CARBOXAMIDES FOR USE IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2010-02-18 WO claimed
US-20100040563-A1 Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products THE PROCTER & GAMBLE COMPANY 2010-02-18 US claimed
CN-1216577-A Detergent compositions containing enduring perfume PROCTER & GAMBLE (US) 1999-05-12 CN claimed
US-12545856-B2 Detergent compositions comprising secondary alkane sultanate, a second anionic surfactant, and alkyl hydroxysultaine cosurfactant CONOPCO, INC. (US) 2026-02-10 US disclosed
US-4496467-A Insect repellent, pheremonal, animal repellent diagnostic and/or aroma augmenting or enhancing compositions and articles containing at least a major proportion of poly(epsilon caprolactone)homopolymers, and having imbedded therein one or more functional INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-29 US disclosed
US-4469613-A SUSTAINED RELEASE OF PERFUME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545856-B2 Detergent compositions comprising secondary alkane sultanate, a second anionic surfactant, and alkyl hydroxysultaine cosurfactant SCD, STS, FFAR2 HIF1A 2773/4885SMN1; SMN2 610/4885SLC6A2 1058/4885
US-20100040563-A1 Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products CUTA, TAS2R8, TAS2R38 HIF1A 685/4885SMN1; SMN2 3078/4885SLC6A2 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.