Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27018562 | 0.88 | ELANE (0.42) | ELANEFABP7FABP3FABP5KDM4E | |
| SCHEMBL7714404 | 0.83 | ELANE (0.41) | ELANEFABP7FABP3FABP5KDM4E | |
| SCHEMBL7866345 | 0.82 | FABP7 (0.50) | ELANEFABP7FABP3FABP5KDM4E | |
| SCHEMBL20382703 | 0.80 | ELANE (0.47) | ELANEKDM4EHSD17B10HPGDBCHE | |
| SCHEMBL29391949 | 0.80 | CA12 (0.48) | ELANEKDM4EHSD17B10HPGDMTNR1A | |
| SCHEMBL27259478 | 0.80 | ELANE (0.47) | ELANEKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL8101855 | 0.80 | ELANE (0.47) | ELANEKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL14894503 | 0.80 | ELANE (0.47) | ELANEKDM4EHSD17B10HPGDMTNR1A | |
| SCHEMBL30711978 | 0.80 | CA12 (0.48) | ELANEKDM4EHSD17B10HPGDMTNR1A | |
| SCHEMBL26667020 | 0.79 | KDM4E (0.59) | FABP7FABP3FABP5KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020041976-A1 | Novel compounds and their manufacture and use | ANDERSON SALLY (GB) | 2002-04-11 | — | — | US | disclosed |
| EP-1138713-A2 | Compounds and their manufacture and use | Sharp Kabushiki Kaisha (JP) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020041976-A1 | Novel compounds and their manufacture and use | TRPC3, SLC43A1, TDO2 | ELANE 2072/4885FABP7 1442/4885FABP3 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.