Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391875 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A3MEN1KMT2ASLC6A2 | |
| SCHEMBL4398580 | 0.95 | SLC6A4 (0.57) | SLC6A4SLC6A3MEN1KMT2ASLC6A2 | |
| SCHEMBL7531306 | 0.82 | SLC6A4 (0.73) | SLC6A4SLC6A3MEN1KMT2ASLC6A2 | |
| Dimethylamine SCHEMBL4391881 | 0.80 | MEN1 (0.46) | SLC6A4SLC6A3MEN1KMT2ASLC22A1 | |
| Dimethylamine SCHEMBL4398587 | 0.74 | SLC22A1 (0.42) | SLC6A4SLC6A3MEN1KMT2ASLC6A2 | |
| SCHEMBL3517244 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517909 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517911 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517239 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517241 | 0.72 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988398-B1 | Immunoassay for tramadol and its major metabolites | RANDOX LAB LTD (GB) | 2009-12-16 | — | — | EP | claimed |
| EP-1988398-B1 | Immunoassay for tramadol and its major metabolites | RANDOX LAB LTD (GB) | 2009-12-16 | — | — | EP | disclosed |
| EP-1988398-A1 | Immunoassay for tramadol and its major metabolites | Randox Laboratories Ltd. (GB) | 2008-11-05 | — | — | EP | disclosed |