Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532812 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL7537162 | 0.84 | MAPT (0.57) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL2157542 | 0.83 | NPSR1 (0.46) | KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2157930 | 0.77 | ACLY (0.55) | KDM4E | |
| SCHEMBL2158668 | 0.75 | ACLY (0.67) | KDM4E | |
| SCHEMBL7532788 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL2158516 | 0.75 | NPSR1 (0.52) | KDM4EALDH1A1HPGD | |
| SCHEMBL7534435 | 0.74 | MEN1 (0.47) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL7537982 | 0.74 | HTT (0.53) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL7534244 | 0.74 | MEN1 (0.59) | MAPTMEN1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |