Mexacarbate

Mexacarbate

SCHEMBL7532034

CNC(=O)O.CNC(=O)Oc1cc(C)c(N(C)C)c(C)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 4/20 0.45
ACHE P22303 6/20 0.42
BCHE P06276 4/20 0.42
KMT2A Q03164 5/20 0.41
MEN1 O00255 3/20 0.41
POLB P06746 2/20 0.41
GAA P10253 1/20 0.41
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
GFER P55789 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mexacarbate SCHEMBL121459 0.96 ACHE (0.44) RAF1ACHEBCHEKMT2AMEN1
Mexacarbate SCHEMBL6738142 0.96 ACHE (0.44) RAF1ACHEBCHEKMT2AMEN1
SCHEMBL119743 0.81 RAF1 (0.48) RAF1ACHEBCHEKMT2AGAA
Aminocarb SCHEMBL7529045 0.81 ACHE (0.45) RAF1ACHEBCHEKMT2AKDM4E
3,5-Dimethylphenyl Methylcarbamate SCHEMBL6736279 0.78 RAF1 (0.43) RAF1ACHEBCHEKMT2AMEN1
Methiocarb SCHEMBL7530314 0.78 RAF1 (0.44) RAF1ACHEBCHEKMT2AMEN1
SCHEMBL11483381 0.78 KMT2A (0.47) ACHEBCHEKMT2AMEN1POLB
SCHEMBL6733303 0.77 TDP1 (0.50) RAF1ACHEBCHEL3MBTL1ALDH1A1
Aminocarb SCHEMBL6740142 0.77 ACHE (0.47) RAF1ACHEBCHEKMT2AKDM4E
Aminocarb SCHEMBL119059 0.77 ACHE (0.47) RAF1ACHEBCHEKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906014-B1 Shaped bodies which release agrochemicals BAYER AG (DE) 2002-03-27 EP disclosed
EP-0906014-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AG (DE) 1999-04-07 EP disclosed
EP-0861024-A1 POLYSACCHARIDE ETHER ESTERS WHICH RELEASE ACTIVE INGREDIENTS BAYER AG (DE) 1998-09-02 EP disclosed
WO-1997046094-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-11 WO disclosed
WO-1997017847-A1 POLYSACCHARIDE ETHER ESTERS WHICH RELEASE ACTIVE INGREDIENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-05-22 WO disclosed
EP-0124404-A1 Insecticide collar and method for its manufacture Rombi, Max André (FR) 1984-11-07 EP disclosed