Mexacarbate

Mexacarbate

SCHEMBL6738142

CNC(=O)Oc1cc(C)c(N(C)C)c(C)c1.CNC(=O)Oc1cc(C)c(N(C)C)c(C)c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.44
BCHE P06276 7/20 0.44
RAF1 P04049 4/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mexacarbate SCHEMBL121459 1.00 ACHE (0.44) ACHEBCHERAF1KMT2AMEN1
Mexacarbate SCHEMBL7532034 0.96 RAF1 (0.45) ACHEBCHERAF1KMT2AMEN1
SCHEMBL119743 0.84 RAF1 (0.48) ACHEBCHERAF1KMT2AGAA
SCHEMBL11483381 0.81 KMT2A (0.47) ACHEBCHEKMT2AMEN1POLB
Aminocarb SCHEMBL31598882 0.80 ACHE (0.47) ACHEBCHERAF1KMT2AKDM4E
Aminocarb SCHEMBL119059 0.80 ACHE (0.47) ACHEBCHERAF1KMT2AKDM4E
Aminocarb SCHEMBL6740142 0.80 ACHE (0.47) ACHEBCHERAF1KMT2AKDM4E
SCHEMBL11786409 0.80 ACHE (0.40) ACHEBCHERAF1KMT2AKDM4E
SCHEMBL7649071 0.79 LMNA (0.45) ACHEBCHERAF1GAAKDM4E
SCHEMBL11725210 0.79 RAF1 (0.47) ACHEBCHERAF1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB ACHE 250/4885BCHE 362/4885RAF1 4679/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB ACHE 251/4885BCHE 379/4885RAF1 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.