SCHEMBL7532095

SCHEMBL7532095

CC(CN(C)C)Oc1cccc(OC(C)CN(C)C)n1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
HTR7 P34969 2/20 0.38
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 1/20 0.37
CHEK1 O14757 5/20 0.36
CHEK2 O96017 2/20 0.36
MCHR1 Q99705 1/20 0.36
CDK1 P06493 1/20 0.35
KCNH2 Q12809 1/20 0.35
TOP1 P11387 1/20 0.35
TSHR P16473 1/20 0.34
CYP3A4 P08684 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11580183 0.81 SCN1A (0.41) HTR7CYP2D6MCHR1TSHR
SCHEMBL19533013 0.76 MCHR1 (0.49) HTR2AHRH1TDP1ALDH1A1HSD17B10
SCHEMBL3320715 0.74 PDE3B (0.34) CHEK1CHEK2TOP1
SCHEMBL12499904 0.74 CHEK1 (0.42) CHEK1CHEK2KCNH2
SCHEMBL12411129 0.73 MAPK8 (0.41) CHEK1CHEK2
SCHEMBL2523502 0.72 KMT2A (0.42) ALDH1A1CYP2D6CYP2C19MCHR1TSHR
SCHEMBL17442425 0.70 GBA1 (0.38) HTR2AHRH1ALDH1A1CYP2D6CHEK1
SCHEMBL7532100 0.69 HTR7 (0.34) HTR7MCHR1
SCHEMBL14577984 0.69 HTR2A (0.41) HTR2AHRH1TDP1ALDH1A1HSD17B10
SCHEMBL21207905 0.69 ACHE (0.46) ALDH1A1MCHR1TOP1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4090988-A Polyurethane foam preparation using pyridine ether catalysts OLIN CORPORATION (US) 1978-05-23 US claimed
US-20020056675-A1 Gas vent filter construction incorporating a hollow fiber membrane assembly MILLIPORE CORPORATION 2002-05-16 US disclosed
WO-2002018037-A2 GAS VENT FILTER CONSTRUCTION INCORPORATING A HOLLOW FIBER MEMBRANE ASSEMBLY MILLIPORE CORPORATION (US) 2002-03-07 WO disclosed
US-4369605-A Methods for preparing tube sheets for permeators having hollow fiber membranes MONSANTO COMPANY (US) 1983-01-25 US disclosed
US-4323454-A CURED EPOXY RESIN, FILLER, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US disclosed
US-4323453-A EPOXY RESIN CURED WITH AN IMIDAZOLE, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US disclosed
EP-0044193-A1 Methods for preparing tube sheets for permeators having hollow fiber membranes MONSANTO COMPANY (US) 1982-01-20 EP disclosed
US-4090988-A Polyurethane foam preparation using pyridine ether catalysts OLIN CORPORATION (US) 1978-05-23 US disclosed
US-4048107-A Polyurethane foam preparation using amio acetal catalyst OLIN CORPORATION (US) 1977-09-13 US disclosed