Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 10/20 | 0.49 |
| ▸ | NPY1R | P25929 | 7/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.49 |
| ▸ | NPY2R | P49146 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535309 | 0.87 | KISS1R (0.54) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7529600 | 0.87 | KISS1R (0.56) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7525098 | 0.87 | KISS1R (0.54) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7532875 | 0.84 | KISS1R (0.54) | KISS1RRAB9ANPY4RNPY1RNPY5R | |
| SCHEMBL7113842 | 0.84 | NPY4R (0.44) | KISS1RNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL27319796 | 0.84 | SSTR3 (0.52) | KISS1RNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL521932 | 0.84 | SSTR3 (0.52) | KISS1RNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7106396 | 0.84 | SSTR3 (0.52) | KISS1RNPC1RAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL566787 | 0.83 | SSTR3 (0.51) | KISS1RNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6800534 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TP53BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |