SCHEMBL7532289

SCHEMBL7532289

CS(=O)(=O)Nc1ccc(NC(=O)Nc2ccc(C[C@@H](CO)NC[C@@H](COc3ccccc3)OC(=O)C(F)(F)F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 16/20 0.58
ADRB1 P08588 14/20 0.58
ADRB2 P07550 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6539448 0.95 ADRB3 (0.58) ADRB3ADRB1ADRB2
SCHEMBL6538790 0.94 ADRB3 (0.56) ADRB3ADRB1ADRB2
SCHEMBL6539718 0.89 ADRB3 (0.61) ADRB3ADRB1
Trifluoroacetic Acid SCHEMBL6538796 0.87 ADRB3 (0.75) ADRB3ADRB1ADRB2
SCHEMBL6541344 0.87 ADRB3 (0.58) ADRB3ADRB1
SCHEMBL6539506 0.86 ADRB3 (0.59) ADRB3ADRB1
SCHEMBL6539720 0.86 ADRB3 (0.60) ADRB3ADRB1
SCHEMBL6539488 0.86 ADRB3 (0.57) ADRB3ADRB1
SCHEMBL6539964 0.86 ADRB3 (0.57) ADRB3ADRB1
SCHEMBL6539734 0.85 ADRB3 (0.62) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002024635-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-03-28 WO disclosed