Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539241 | 0.94 | ADRB3 (0.60) | ADRB3ADRB1MAPTMEN1KMT2A | |
| SCHEMBL6538734 | 0.92 | ADRB3 (0.54) | ADRB3ADRB1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6541344 | 0.89 | ADRB3 (0.58) | ADRB3ADRB1MEN1KMT2ANPC1 | |
| SCHEMBL6539964 | 0.89 | ADRB3 (0.57) | ADRB3ADRB1 | |
| SCHEMBL6539718 | 0.88 | ADRB3 (0.61) | ADRB3ADRB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6539092 | 0.88 | ADRB3 (0.62) | ADRB3ADRB1MAPT | |
| Trifluoroacetic Acid SCHEMBL6539492 | 0.88 | ADRB3 (0.73) | ADRB3ADRB1MAPTNAMPTMEN1 | |
| SCHEMBL7532289 | 0.86 | ADRB3 (0.58) | ADRB3ADRB1 | |
| SCHEMBL6539506 | 0.86 | ADRB3 (0.59) | ADRB3ADRB1NPC1RAB9A | |
| SCHEMBL6539720 | 0.85 | ADRB3 (0.60) | ADRB3ADRB1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |