Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532294 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTR1AHPGDHTR2C | |
| SCHEMBL141596 | 0.81 | CA12 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TPMT | |
| SCHEMBL141595 | 0.81 | CA12 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TPMT | |
| SCHEMBL141594 | 0.81 | CA12 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TPMT | |
| Hydrochloric Acid SCHEMBL6782887 | 0.79 | CA12 (0.61) | ALDH1A1KDM4EHPGDHSD17B10TPMT | |
| SCHEMBL9079788 | 0.78 | HTT (0.65) | ALDH1A1KDM4EHPGDHSD17B10ABCG2 | |
| SCHEMBL2352404 | 0.78 | HTT (0.65) | ALDH1A1KDM4EHPGDHSD17B10ABCG2 | |
| SCHEMBL10634998 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TUBB1TPMTHTT | |
| SCHEMBL16294733 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDTPMTHTTCYP1A2 | |
| SCHEMBL8646387 | 0.77 | TUBB4A (0.56) | ALDH1A1KDM4EHTR1AHPGDHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022122-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2002-03-21 | — | — | WO | claimed |
| CN-104726399-B | The application of ethyl ρ-methoxy cinnamate and its derivative in stem cells self-renewal and multipotency is maintained | 东北师范大学 | 2018-05-29 | — | — | CN | disclosed |
| WO-2002022122-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2002-03-21 | — | — | WO | disclosed |