Ether

Ether

SCHEMBL7532302

CCOCC.CN(C)CCOC(=O)C(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CHRNB2 P17787 1/20 0.48
CHRM3 P20309 1/20 0.48
CHRNA4 P43681 1/20 0.48
DNM1 Q05193 1/20 0.43
ALDH1A1 P00352 4/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 2/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
BCHE P06276 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PHLPP2 Q6ZVD8 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4331422 0.82 CA12 (0.52) CHRM1CHRM2CHRM4CHRM5CHRNB2
Ether SCHEMBL28178802 0.81 THRB (0.65) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL2176180 0.77 THRB (0.63) ALDH1A1THRBSMN1; SMN2TSHR
SCHEMBL31299541 0.76 KDM4E (0.47) CHRM1CHRM2CHRM4CHRM5CHRNB2
Methacrylic Acid SCHEMBL11969913 0.73 THRB (0.48) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL28365017 0.73 DNM1 (0.61) CHRM1CHRM2CHRM4CHRM5CHRNB2
Methacrylic Acid SCHEMBL319586 0.73 THRB (0.48) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL9549797 0.73 CHRM1 (0.47) CHRM1CHRM2CHRM3ALDH1A1KDM4E
SCHEMBL16203714 0.73 CHRM1 (0.58) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL29107337 0.72 CHRM1 (0.52) CHRM1CHRM2CHRM4CHRM5CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189607-A2 ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES Washington State University Research Foundation (US) 2002-03-27 EP disclosed
WO-2000059492-A2 ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-10-12 WO disclosed