Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539866 | 0.95 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1ADORA2AMAPTLMNA | |
| SCHEMBL69960 | 0.89 | ALDH1A1 (0.85) | ALDH1A1L3MBTL1MAPTLMNAMAPK1 | |
| SCHEMBL69132 | 0.83 | ALDH1A1 (0.88) | ALDH1A1L3MBTL1MAPTLMNAMAPK1 | |
| SCHEMBL5866519 | 0.83 | ALDH1A1 (0.81) | ALDH1A1L3MBTL1MAPTLMNAPOLB | |
| SCHEMBL122019 | 0.83 | ADORA2A (0.83) | ALDH1A1L3MBTL1ADORA2AMAPTLMNA | |
| SCHEMBL27880004 | 0.83 | ADORA2A (0.65) | ALDH1A1L3MBTL1ADORA2AMAPTLMNA | |
| SCHEMBL461660 | 0.82 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTLMNAMAPK1 | |
| Anthraquinone SCHEMBL8941397 | 0.82 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTLMNAMAPK1 | |
| SCHEMBL17744822 | 0.82 | MMP2 (0.57) | ALDH1A1L3MBTL1ADORA2AMAPTLMNA | |
| SCHEMBL7540373 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1ADORA2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030906-A1 | ANTI-TUMOUR COMPOUNDS | LA TROBE UNIVERSITY (AU) | 2002-04-18 | — | — | WO | disclosed |