Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7532484

C1=CCC([Zr](=C(c2ccccc2)c2ccccc2)C2c3ccccc3-c3ccccc32)=C1.[Cl-].[Cl-].[Cl-].[Cl-].[Zr+4]C1C2C=CC=CC2C2CCCCC12

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7647543 0.84
SCHEMBL813468 0.83 MEN1 (0.30)
Hydrochloric Acid SCHEMBL9064568 0.82
Hydrochloric Acid SCHEMBL7617603 0.82
SCHEMBL8148057 0.74 RAB9A (0.33)
Hydrochloric Acid SCHEMBL17743533 0.73 RAB9A (0.32)
SCHEMBL6890632 0.72 POLB (0.30)
SCHEMBL8900942 0.72 POLB (0.30)
SCHEMBL6890636 0.72 POLB (0.30)
SCHEMBL8160847 0.72 GAA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384556-A1 PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY W. R. Grace & Co.-Conn (US) 2024-06-19 EP disclosed
WO-2023177433-A1 PROCESS FOR PRODUCING HEAT TREATED SUPPORTED ALUMINOXANES IN AN ALIPHATIC SOLVENT USING SOLID ALUMINOXANES W.R. GRACE & CO.-CONN. (US) 2023-09-21 WO disclosed
WO-2023178116-A1 SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM W. R. GRACE & CO.-CONN (US) 2023-09-21 WO disclosed
WO-2023069328-A1 PROCESS FOR PRODUCING A SINGLE SITE CATALYST W.R. GRACE & CO.-CONN. (US) 2023-04-27 WO disclosed
WO-2023018671-A1 PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY W.R. GRACE & CO.-CONN. (US) 2023-02-16 WO disclosed
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP disclosed
US-20020006863-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2002-01-17 US disclosed
US-20010018395-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2001-08-30 US disclosed
EP-0830385-B1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS GRACE W R & CO (US) 2000-12-27 EP disclosed
EP-0965601-A1 Mixed catalyst composition for the production of olefin polymers UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-12-22 EP disclosed
US-5939347-A Supported catalytic activator W.R. GRACE & CO. -CONN. (US) 1999-08-17 US disclosed
US-5885924-A REACTING A CARRIER CONTAINING REACTIVE FUNCTIONALITIES, E.G., HYDROXYL CONTAINING SILICA, WITH HALOGENATED ORGANIC COMPOUNDS, E.G., FLUOROSUBSTITUTED PHENOLS, IN THE PRESENCE OF A BASE W. R. GRACE & CO.-CONN. (US) 1999-03-23 US disclosed
EP-0784062-A2 Process for production of long-chain branched polyolefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-07-16 EP disclosed
EP-0770629-A2 A process for preparing an in situ polyethylene blend UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-05-02 EP disclosed
EP-0593083-B1 Gas phase polymerization reaction utilizing soluble unsupported catalysts UNION CARBIDE CHEM PLASTIC (US) 1996-05-01 EP disclosed
US-5317036-A Continuous catalytic vapor phase polymerization of olefins UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-05-31 US disclosed
EP-0593083-A1 Gas phase polymerization reaction utilizing soluble unsupported catalysts UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-20 EP disclosed