Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | STS | P08842 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426680 | 0.89 | HDAC4 (0.61) | HDAC4KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8366262 | 0.89 | KMT2A (0.70) | HDAC4KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17572994 | 0.88 | HDAC4 (0.60) | HDAC4KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4603719 | 0.88 | HDAC4 (0.63) | HDAC4KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL25401822 | 0.88 | HDAC4 (0.60) | HDAC4KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13199301 | 0.87 | KDM4E (0.68) | HDAC4KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL27570374 | 0.87 | HDAC4 (0.55) | HDAC4KMT2AALDH1A1STSCNR1 | |
| SCHEMBL28457523 | 0.86 | ALDH1A1 (0.70) | HDAC4KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1712156 | 0.86 | HDAC4 (0.55) | HDAC4KMT2AALDH1A1CNR1CNR2 | |
| SCHEMBL17729070 | 0.86 | USP30 (0.66) | HDAC4KMT2AMEN1SMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-B | Tripeptide epoxy ketone compound constructed by heterocycle, preparation and application | 浙江大学 | 2020-08-11 | — | — | CN | disclosed |
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |