Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515339 | 0.88 | MAPT (0.56) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL21300617 | 0.88 | BCHE (0.67) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL18623128 | 0.84 | HTR1A (0.68) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL27436345 | 0.82 | HTR1A (0.56) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL14176616 | 0.81 | HTR1A (0.70) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL12843212 | 0.81 | BCHE (0.60) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6312645 | 0.81 | HTR1A (0.63) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10447265 | 0.81 | NPC1 (0.52) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4770649 | 0.80 | ABCB1 (0.56) | BCHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7293001 | 0.80 | BCHE (0.58) | BCHEHTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |