Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329056 | 1.00 | REN (0.67) | REN | |
| SCHEMBL7485961 | 0.94 | REN (0.68) | REN | |
| SCHEMBL7485955 | 0.94 | REN (0.68) | REN | |
| Remikiren SCHEMBL9556439 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL22263508 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL9556708 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL12921156 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL156393 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL7303589 | 0.93 | REN (0.76) | REN | |
| Remikiren SCHEMBL8352030 | 0.93 | REN (0.76) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |