Remikiren

Remikiren

SCHEMBL156393

CC(C)(C)S(=O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Remikiren SCHEMBL22263508 1.00 REN (0.76) REN
Remikiren SCHEMBL12921169 1.00 REN (0.76) REN
Remikiren SCHEMBL12921156 1.00 REN (0.76) REN
Remikiren SCHEMBL8352030 1.00 REN (0.76) REN
Remikiren SCHEMBL8352292 1.00 REN (0.76) REN
Remikiren SCHEMBL9556439 1.00 REN (0.76) REN
Remikiren SCHEMBL7303589 1.00 REN (0.76) REN
Remikiren SCHEMBL9556708 1.00 REN (0.76) REN
SCHEMBL7328547 0.99 REN (0.74) REN
SCHEMBL7292222 0.99 REN (0.74) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206779-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF UNIVERSIDAD DE CHILE (CL) 2025-06-26 US claimed
WO-2025050228-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDE OR A COMBINATION OF PEPTIDES AGONISTIC TO THE MAS, AT1 AND AT2 RECEPTORS PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) 2025-03-13 WO claimed
US-20250082608-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2025-03-13 US claimed
EP-4448096-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE Singapore Health Services Pte. Ltd. (SG) 2024-10-23 EP claimed
EP-4337675-A1 ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Universidad De Chile (CL) 2024-03-20 EP claimed
US-20240002935-A1 GENETIC METHOD FOR DIAGNOSIS AND TREATMENT OF PRE AND POST CORONAVIRUS INFECTIONS GENETICURE INC. 2024-01-04 US claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 WO claimed
WO-2023111196-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE. LTD. (SG) 2023-06-22 WO claimed
EP-4132653-A1 GENETIC METHOD FOR DIAGNOSIS AND TREATMENT OF PRE AND POST CORONAVIRUS INFECTIONS Geneticure Inc. (US) 2023-02-15 EP claimed
WO-2022265697-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND METHODS FOR SAME Tiger Development, LLC (US) 2022-12-22 WO claimed
WO-2005037317-A2 MAST CELL-DERIVED RENIN CORNELL RESEARCH FOUNDATION, INC. (US) 2005-04-28 WO claimed
WO-2005025673-A1 MULTI-SYSTEM THERAPY FOR DIABETES, THE METABOLIC SYNDROME AND OBESITY COMPRISING A HYPOGLYCEMIC AGENT FOLLI FRANCO (IT) 2005-03-24 WO claimed
US-20050065184-A1 Method of reducing the risk of oxidative stress AAIPHARMA INC. 2005-03-24 US claimed
US-20050054731-A1 Includes a biguanide hypoglycemic agent, a lipid lowering agent, a blood pressure lowering agent and, preferably, an anti-platelet agent FOLLI FRANCO (IT) 2005-03-10 US claimed
WO-2005020984-A2 METHOD OF REDUCING THE RISK OF OXIDATIVE STRESS AAIPHARMA INC. (US) 2005-03-10 WO claimed
US-20040266743-A1 Combination of an aldosterone receptor antagonist and a renin inhibitor PHARMACIA CORPORATION 2004-12-30 US claimed
WO-2004100871-A2 COMBINATION OF AN ALDOSTERONE RECEPTOR ANTAGONIST AND A RENIN INHIBITOR PHARMACIA CORPORATION (US) 2004-11-25 WO claimed
US-5981470-A ADMINISTERING PHARMACEUTICAL AGENT SELECTED FROM THE GROUP CONSISTING OF AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR, AN ANGIOTENSIN II-RECEPTOR ANTAGONIST, A RENIN INHIBITOR, AND AN ANGIOTENSIN II-RECEPTOR EXPRESSION INHIBITOR THE UNIVERSITY OF BIRMINGHAM (GB) 1999-11-09 US claimed
EP-0764021-A1 UTERINE FIBROID TREATMENT THE UNIVERSITY OF BIRMINGHAM (GB) 1997-03-26 EP claimed
WO-1995033454-A1 UTERINE FIBROID TREATMENT THE UNIVERSITY OF BIRMINGHAM (GB) 1995-12-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266743-A1 Combination of an aldosterone receptor antagonist and a renin inhibitor REN, AGTR1, AGTR2 REN 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.