Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 4/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076276 | 0.74 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1LIPGNR5A1NR5A2 | |
| SCHEMBL11278522 | 0.74 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1LIPGNR5A1NR5A2 | |
| SCHEMBL27472563 | 0.73 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LIPGNR5A1NR5A2 | |
| SCHEMBL15655439 | 0.72 | PRCP (0.36) | CYSLTR2CYSLTR1 | |
| SCHEMBL27472566 | 0.72 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1LIPGNR5A1NR5A2 | |
| SCHEMBL8558033 | 0.70 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LIPGBIDMCL1 | |
| SCHEMBL12645209 | 0.69 | SPHK1 (0.45) | SLC6A2HTR2AHTR2CSLC6A4THRA | |
| SCHEMBL8756270 | 0.69 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1LIPGBIDMCL1 | |
| SCHEMBL7532693 | 0.69 | LIPG (0.45) | LIPG | |
| Cyclohexanol SCHEMBL29163067 | 0.68 | BID (0.48) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239110-A | Phenylcyclohexanol derivatives as agents for treating CNS disorders | STERLING WINTHROP, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |