Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190615 | 0.83 | — | — | |
| SCHEMBL9187362 | 0.83 | — | — | |
| SCHEMBL9193275 | 0.81 | SLC6A2 (0.33) | — | |
| SCHEMBL28431231 | 0.79 | LIPG (0.43) | LIPGNR1H2NR1H3 | |
| SCHEMBL16593922 | 0.74 | CNR2 (0.42) | LIPG | |
| SCHEMBL9307506 | 0.73 | LIPG (0.40) | LIPGNR1H2NR1H3 | |
| SCHEMBL9352973 | 0.73 | CNR2 (0.40) | LIPG | |
| SCHEMBL7532691 | 0.72 | HTR2A (0.51) | — | |
| SCHEMBL1343771 | 0.72 | LIPG (0.69) | LIPGNR1H2NR1H3 | |
| SCHEMBL15809821 | 0.72 | LIPG (0.69) | LIPGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239110-A | Phenylcyclohexanol derivatives as agents for treating CNS disorders | STERLING WINTHROP, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0063793-A2 | (Arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-11-03 | — | — | EP | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4313959-A | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-02-02 | — | — | US | disclosed |