⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425819 | 0.81 | — | — | |
| SCHEMBL9277152 | 0.79 | — | — | |
| SCHEMBL2173006 | 0.79 | — | — | |
| SCHEMBL3118880 | 0.77 | — | — | |
| SCHEMBL4354473 | 0.77 | — | — | |
| SCHEMBL2394683 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL28244519 | 0.77 | — | — | |
| SCHEMBL2053624 | 0.76 | — | — | |
| SCHEMBL11082013 | 0.75 | HTT (0.32) | — | |
| SCHEMBL19222388 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891974-B1 | Process for producing chromans | KURARAY CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6133471-A | Process for producing chromans | KURARAY CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-6130341-A | Process for producing chromans | KURARAY CO., LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0645383-B1 | Process for producing chromanes | KURARAY CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0891974-A1 | Process for producing chromans | KURARAY CO., LTD. (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5495026-A | Process for producing chroman | KURARAY COMPANY LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0645383-A1 | Process for producing chroman | KURARAY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |
| US-5230841-A | Heating filler to form pores | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |