SCHEMBL11082013

SCHEMBL11082013

NC(=O)CC1=CC=CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050515 0.83
SCHEMBL2394683 0.82 ALDH1A1 (0.33) HTT
SCHEMBL28244519 0.82
SCHEMBL11401504 0.80
SCHEMBL3328517 0.79 HTT (0.32) HTTCA2
SCHEMBL19222388 0.77
SCHEMBL7532786 0.75
SCHEMBL4354473 0.75
SCHEMBL9425819 0.74
SCHEMBL4230150 0.74 MTNR1A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460600-A Adjacently substituted ketal derivatives of cycloalkane-amide analgesics THE UPJOHN COMPANY (US) 1984-07-17 US disclosed