SCHEMBL7532808

SCHEMBL7532808

CC(c1ccc(O)cc1)c1ccc(O)cc1.Cc1ccc(C(C)(C)c2ccc(C)c(O)c2C)c(C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.52
ESR2 Q92731 9/20 0.52
PDCD1 Q15116 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
CYP3A4 P08684 3/20 0.34
AR P10275 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A3 Q01959 2/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTR6 P50406 1/20 0.34
ESRRG P62508 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PTGS1 P23219 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
TRPA1 O75762 1/20 0.33
CACNA1C Q13936 1/20 0.33
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376862 0.82 GABRA1 (0.45) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL920467 0.82 GABRA1 (0.45) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL10593295 0.72 ESR1 (1.00) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL29713170 0.72 GABRA1 (0.39) ARPTGS1GABRA1GABRB2TRPA1
SCHEMBL26946 0.72 ESR1 (1.00) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL7919913 0.71 ESR1 (0.70) ESR1ESR2PDCD1CD274CYP3A4
Bisphenol A SCHEMBL27987462 0.71 ESR1 (0.70) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL4905749 0.71 ESR1 (0.70) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL580699 0.70 GABRA1 (0.56) CYP3A4TSHRHSD17B10PTGS1GABRA1
SCHEMBL29644929 0.70 GABRA1 (0.56) CYP3A4TSHRHSD17B10PTGS1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002008821-A1 THERMOCHROMIC COMPOSITION SKYRAD LTD. (IL) 2002-01-31 WO claimed