Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022902 | 0.87 | TSHR (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5014838 | 0.82 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28821508 | 0.78 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27461420 | 0.77 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5014818 | 0.77 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5598534 | 0.72 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19566738 | 0.72 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL526308 | 0.72 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12589316 | 0.71 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL244114 | 0.71 | TSHR (0.95) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685506-B1 | Method for the preparation of (meth)acryloxyalkyl group-containing linear organopolysiloxane | SHINETSU CHEMICAL CO (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-0624627-B1 | Radiation-curable organopolysiloxane composition | SHINETSU CHEMICAL CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5504234-A | MIXING CYCLIC POLYSILOXANE OLIGOMER HAVING ACRYLOXYALKYL GROUP WITH CATION EXCHANGE RESIN, HEATING TO EFFECT RING-OPENING SILOXANE REARRANGEMENT POLYMERIZATION, REMOVING RESIN | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0685506-A2 | Method for the preparation of (meth)acryloxyalkyl group-containing linear organopolysiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |
| US-5436281-A | Curable films of polysiloxanes with acryloxyalkyl terminal groups to form releasing surfaces | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0624627-A2 | Radiation-curable organopolysiloxane composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5306558-A | Double-layered rubber laminate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| US-4987180-A | SOFTNESS, ELASTIC RESILIENCE, WINDPROOFING, WASHFASTNESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4985155-A | Graft Polymer of an Acrylate on a Polysiloxane | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0233752-A2 | A method for the preparation of a cured organopolysiloxane composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |