SCHEMBL7533388

SCHEMBL7533388

O=P(Nc1ccccc1)(c1ccccc1)c1ccc(P(=O)(Nc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.58
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.47
NPSR1 Q6W5P4 1/20 0.45
MAPT P10636 1/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RECQL P46063 1/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
CA5A P35218 2/20 0.42
TSHR P16473 3/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALOX12 P18054 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16868500 0.98 KCNA5 (0.59) KCNA5LMNAKDM4ENPSR1MAPT
Hydrochloric Acid SCHEMBL28020743 0.95 KCNA5 (0.58) KCNA5LMNAKDM4ENPSR1MAPT
SCHEMBL17289225 0.87 HPGD (0.53) KCNA5LMNAKDM4ENPSR1MAPT
SCHEMBL4585629 0.85 ESR1 (0.55) KCNA5LMNAMAPTALDH1A1MEN1
SCHEMBL10051662 0.83 KCNA5 (0.47) KCNA5LMNAKDM4EMAPTALDH1A1
SCHEMBL17289231 0.82 RAB9A (0.49) KCNA5LMNAMAPTALDH1A1MEN1
SCHEMBL17289238 0.82 HPGD (0.65) KCNA5LMNAKDM4ENPSR1MAPT
SCHEMBL4584942 0.78 KCNA5 (0.59) KCNA5LMNAMAPTALDH1A1MEN1
SCHEMBL13043277 0.78 KDM4E (0.48) KCNA5LMNAKDM4ENPSR1ALDH1A1
SCHEMBL17288988 0.77 KCNA5 (0.46) KCNA5LMNAKDM4ENPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020056675-A1 Gas vent filter construction incorporating a hollow fiber membrane assembly MILLIPORE CORPORATION 2002-05-16 US disclosed
WO-2002018037-A2 GAS VENT FILTER CONSTRUCTION INCORPORATING A HOLLOW FIBER MEMBRANE ASSEMBLY MILLIPORE CORPORATION (US) 2002-03-07 WO disclosed
US-4369605-A Methods for preparing tube sheets for permeators having hollow fiber membranes MONSANTO COMPANY (US) 1983-01-25 US disclosed
US-4323453-A EPOXY RESIN CURED WITH AN IMIDAZOLE, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US disclosed
US-4323454-A CURED EPOXY RESIN, FILLER, HOLLOW FIBERS MONSANTO COMPANY (US) 1982-04-06 US disclosed
EP-0044193-A1 Methods for preparing tube sheets for permeators having hollow fiber membranes MONSANTO COMPANY (US) 1982-01-20 EP disclosed