Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117189 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7410872 | 0.89 | LMNA (0.42) | LMNAITGB3ITGA2BKCNK3MEN1 | |
| SCHEMBL7533390 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7533394 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7532341 | 0.87 | POLB (0.42) | LMNAKCNK3MEN1ALDH1A1KMT2A | |
| SCHEMBL7421599 | 0.87 | SMN1; SMN2 (0.36) | LMNAITGB3ITGA2BKCNK3ALDH1A1 | |
| SCHEMBL7420056 | 0.86 | LMNA (0.33) | LMNAITGB3ITGA2BMEN1ALDH1A1 | |
| SCHEMBL7416655 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2B | |
| SCHEMBL7421037 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2BMEN1ALDH1A1KMT2A | |
| SCHEMBL7418875 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2BMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |