Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538832 | 0.91 | TYR (0.36) | LIPGCYP3A4HSD17B10ALDH1A1MAPT | |
| SCHEMBL10595842 | 0.89 | CYSLTR2 (0.44) | TLR8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL7530621 | 0.85 | KCNH2 (0.38) | LIPGTLR8CYP3A4MAPTKCNH2 | |
| SCHEMBL7056015 | 0.85 | KCNH2 (0.38) | LIPGTLR8CYP3A4MAPTKCNH2 | |
| SCHEMBL7580690 | 0.85 | KCNH2 (0.38) | LIPGTLR8CYP3A4MAPTKCNH2 | |
| SCHEMBL7717379 | 0.83 | KCNH2 (0.37) | LIPGTLR8CYP3A4MAPTKCNH2 | |
| SCHEMBL7572175 | 0.83 | KCNH2 (0.35) | LIPGTLR8KDM4ECYP3A4HSD17B10 | |
| SCHEMBL7536961 | 0.81 | NR1H2 (0.38) | LIPGTLR8KDM4ECYP3A4HSD17B10 | |
| SCHEMBL6512213 | 0.81 | NR1H2 (0.38) | LIPGTLR8KDM4ECYP3A4HSD17B10 | |
| SCHEMBL6513226 | 0.81 | NR1H2 (0.38) | LIPGTLR8KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714298-B1 | Photosensitiser containing phthalocyanine derivative for photodynamic therapy of tumours | QINETIQ LTD (GB) | 2002-04-24 | — | — | EP | disclosed |
| US-6096734-A | ANTITUMOR | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE AND EVALUATION RESEARCH AGENCY (GB) | 2000-08-01 | — | — | US | disclosed |
| US-5834455-A | CANCER PHOTODYNAMIC THERAPY USING A PHTHALOCYANINE DYES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE & EVALUATION RESEARCH AGENCY, DRA (GB) | 1998-11-10 | — | — | US | disclosed |
| WO-1995005818-A1 | PHOTOSENSITIZERS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1995-03-02 | — | — | WO | disclosed |