Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056015 | 0.93 | KCNH2 (0.38) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL7580690 | 0.93 | KCNH2 (0.38) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL7530621 | 0.93 | KCNH2 (0.38) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL7717379 | 0.92 | KCNH2 (0.37) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL7572175 | 0.92 | KCNH2 (0.35) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL7533536 | 0.91 | LIPG (0.34) | TSHRCYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL4522301 | 0.82 | SPHK2 (0.33) | TYRMEN1TSHRKMT2ATP53 | |
| SCHEMBL10595842 | 0.79 | CYSLTR2 (0.44) | MEN1KMT2A | |
| SCHEMBL7595832 | 0.77 | MAPK14 (0.40) | TSHRCYP3A4MAPTLMNAALDH1A1 | |
| SCHEMBL7580698 | 0.75 | MAPK13 (0.39) | TSHRCYP3A4MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714298-B1 | Photosensitiser containing phthalocyanine derivative for photodynamic therapy of tumours | QINETIQ LTD (GB) | 2002-04-24 | — | — | EP | disclosed |
| US-6096734-A | ANTITUMOR | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE AND EVALUATION RESEARCH AGENCY (GB) | 2000-08-01 | — | — | US | disclosed |
| US-5834455-A | CANCER PHOTODYNAMIC THERAPY USING A PHTHALOCYANINE DYES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE & EVALUATION RESEARCH AGENCY, DRA (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0714298-A1 | PHOTOSENSITIZERS | The Secretary of State for Defence (GB) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005818-A1 | PHOTOSENSITIZERS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1995-03-02 | — | — | WO | disclosed |