Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537215 | 0.84 | MAPK8 (0.47) | MAPK8MAPK10ALDH1A1ACLYLMNA | |
| SCHEMBL7530855 | 0.80 | KMT2A (0.49) | NPC1MAPK8MAPK10SMN1; SMN2MCL1 | |
| SCHEMBL8790850 | 0.80 | TSHR (0.53) | MAPK8MAPK10SMN1; SMN2ALDH1A1ACLY | |
| SCHEMBL532975 | 0.79 | ACLY (0.69) | ALDH1A1ACLYLMNAHPGDTSHR | |
| SCHEMBL7538805 | 0.78 | SCN3A (0.48) | RAB9AMAPK8MAPK10ALDH1A1ACLY | |
| SCHEMBL7534437 | 0.78 | KMT2A (0.47) | MAPK8MAPK10SMN1; SMN2MCL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL533067 | 0.77 | ACLY (0.68) | ALDH1A1ACLYLMNAHPGDTSHR | |
| SCHEMBL7531693 | 0.77 | TSHR (0.46) | MAPK8MAPK10SMN1; SMN2MCL1ALDH1A1 | |
| SCHEMBL3657767 | 0.76 | ACLY (0.55) | MAPK8MAPK10ACLYLMNAHPGD | |
| SCHEMBL533066 | 0.76 | ACLY (0.58) | SMN1; SMN2ALDH1A1ACLYLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |