Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531693 | 0.96 | TSHR (0.46) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7534437 | 0.94 | KMT2A (0.47) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7537215 | 0.83 | MAPK8 (0.47) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8790850 | 0.81 | TSHR (0.53) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7533682 | 0.80 | RAB9A (0.56) | TSHRALDH1A1MAPK8MAPK10LMNA | |
| SCHEMBL7532757 | 0.76 | TSHR (0.65) | KMT2ATSHRALDH1A1CYP2C9LMNA | |
| SCHEMBL7533552 | 0.75 | NR1H3 (0.57) | KMT2ATSHRALDH1A1LMNAMEN1 | |
| SCHEMBL7537015 | 0.75 | SMN1; SMN2 (0.53) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL532885 | 0.74 | LMNA (0.78) | KMT2ATSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL2705227 | 0.74 | ALDH1A1 (0.56) | KMT2ATSHRALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |