Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLR1A | O95602 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532790 | 0.90 | TACR3 (0.47) | POLR1ATACR3KCNH2ALDH1A1KDM4E | |
| SCHEMBL7535163 | 0.78 | POLR1A (0.49) | POLR1AALDH1A1KDM4EHTR1BMEN1 | |
| SCHEMBL7532016 | 0.78 | TACR3 (0.36) | POLR1ATACR3KCNH2ALDH1A1KDM4E | |
| SCHEMBL8436963 | 0.75 | POLR1A (0.38) | POLR1ATACR3KCNH2ALDH1A1KDM4E | |
| SCHEMBL10692306 | 0.72 | HTR1B (0.60) | ALDH1A1KDM4EHTR1BADRB2ADRB1 | |
| SCHEMBL4897475 | 0.71 | TACR3 (0.68) | TACR3KCNH2LMNACYP2D6 | |
| SCHEMBL7532784 | 0.69 | HTR1B (0.48) | POLR1AALDH1A1KDM4EHTR1BADRB2 | |
| SCHEMBL23722882 | 0.68 | KDM4E (0.60) | TACR3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7533323 | 0.66 | POLB (0.51) | KCNH2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11197446 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617288-B1 | Long emission wavelength chemiluminescent compounds and their use in test assays | NOVARTIS AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| US-5395752-A | Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994021823-A1 | LONG EMISSION WAVELENGTH CHEMILUMINESCENT COMPOUNDS AND THEIR USE IN TEST ASSAYS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0617288-A2 | Long emission wavelength chemiluminescent compounds and their use in test assays | CIBA-GEIGY AG (CH) | 1994-09-28 | — | — | EP | disclosed |