Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLR1A | O95602 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118784 | 0.82 | KDM4E (0.40) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL8441018 | 0.82 | POLR1A (0.34) | TACR3KCNH2POLR1AKDM4ETLR9 | |
| SCHEMBL7533773 | 0.81 | LMNA (0.38) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL7533878 | 0.78 | POLR1A (0.46) | TACR3KCNH2POLR1ATNKSKDM4E | |
| SCHEMBL7532790 | 0.77 | TACR3 (0.47) | TACR3KCNH2POLR1ATNKSKDM4E | |
| SCHEMBL7538135 | 0.73 | PLA2G2A (0.41) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL9317254 | 0.70 | KDM4E (0.40) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL641602 | 0.69 | ACHE (0.32) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL4413030 | 0.69 | RAB9A (0.39) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL12088068 | 0.68 | HRH3 (0.41) | TACR3KCNH2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617288-B1 | Long emission wavelength chemiluminescent compounds and their use in test assays | NOVARTIS AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| US-5395752-A | Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0617288-A2 | Long emission wavelength chemiluminescent compounds and their use in test assays | CIBA-GEIGY AG (CH) | 1994-09-28 | — | — | EP | disclosed |