Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701112 | 0.70 | TSHR (0.35) | ALDH1A1POLBTDP1 | |
| SCHEMBL8820551 | 0.70 | GRIN2D (0.41) | ALDH1A1GAAMAPT | |
| SCHEMBL10770627 | 0.62 | — | — | |
| SCHEMBL7363085 | 0.61 | SRD5A1 (0.42) | MEN1ALDH1A1POLBGAAMAPT | |
| SCHEMBL831218 | 0.61 | TDP1 (0.37) | MEN1ALDH1A1POLBMAPTRECQL | |
| SCHEMBL7701111 | 0.60 | ALDH1A1 (0.32) | ALDH1A1POLBTDP1 | |
| SCHEMBL11172226 | 0.60 | ALDH1A1 (0.47) | MEN1ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL8677859 | 0.59 | — | — | |
| SCHEMBL8299813 | 0.59 | MEN1 (0.39) | MEN1ALDH1A1POLBGAAMAPT | |
| SCHEMBL10336520 | 0.58 | NPSR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804464-B1 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INT INC (US) | 2002-05-08 | — | — | EP | claimed |