Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831218 | 0.79 | TDP1 (0.37) | TSHRGPR35TDP1POLBALDH1A1 | |
| SCHEMBL17500355 | 0.74 | POLB (0.33) | TDP1POLBALDH1A1HCAR3GABRA1 | |
| SCHEMBL11129605 | 0.71 | TXNRD1 (0.40) | TSHRGPR35TDP1POLBALDH1A1 | |
| SCHEMBL7701111 | 0.71 | ALDH1A1 (0.32) | TDP1POLBALDH1A1GABRA1GABRB2 | |
| SCHEMBL10693919 | 0.70 | TSHR (0.49) | TSHRGPR35TDP1ALDH1A1TXNRD1 | |
| SCHEMBL7534010 | 0.70 | MEN1 (0.31) | TDP1POLBALDH1A1 | |
| SCHEMBL18478 | 0.70 | TSHR (0.42) | TSHRGPR35TDP1POLBALDH1A1 | |
| SCHEMBL8927043 | 0.69 | ALDH1A1 (0.37) | TSHRTDP1POLBALDH1A1HCAR3 | |
| SCHEMBL2289877 | 0.68 | TSHR (0.50) | TSHRGPR35TDP1ALDH1A1TXNRD1 | |
| SCHEMBL301081 | 0.68 | TSHR (0.41) | TSHRGPR35TDP1ALDH1A1TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339177-B1 | TO INHIBIT OLEFIN POLYMERIZATION BY DEACTIVATING RADICALS THAT LEAD TO POLYMERIZATION | SEA LION TECHNOLOGY, INC. | 2002-01-15 | — | — | US | disclosed |