SCHEMBL7534026

SCHEMBL7534026

O=C(O)c1c2ccccc2nc2ccc3ccccc3c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.51
DHODH Q02127 4/20 0.49
LMNA P02545 1/20 0.49
TSHR P16473 1/20 0.47
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
CYP2C19 P33261 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CDK4 P11802 1/20 0.46
CCND1 P24385 1/20 0.46
MGAM O43451 1/20 0.44
WDR5 P61964 1/20 0.44
CYP2D6 P10635 1/20 0.44
TYMS P04818 2/20 0.44
LDHA P00338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534314 0.87 CDK4 (0.44) PDE10ADHODHLMNATSHRKMT2A
SCHEMBL641899 0.81 PDE10A (0.66) PDE10ADHODHLMNATSHRKMT2A
SCHEMBL29377848 0.81 PDE10A (0.66) PDE10ADHODHLMNATSHRKMT2A
SCHEMBL14917525 0.79 DHODH (0.53) PDE10ADHODHLMNATSHRKMT2A
Hydrochloric Acid SCHEMBL1603404 0.79 PDE10A (0.63) PDE10ADHODHLMNATSHRKMT2A
Iodide SCHEMBL8029601 0.79 PDE10A (0.63) PDE10ADHODHLMNATSHRKMT2A
Hydrochloric Acid SCHEMBL9597551 0.79 PDE10A (0.63) PDE10ADHODHLMNATSHRKMT2A
Water SCHEMBL2991911 0.79 PDE10A (0.63) PDE10ADHODHLMNATSHRKMT2A
Iodide SCHEMBL8029606 0.79 PDE10A (0.63) PDE10ADHODHLMNATSHRKMT2A
SCHEMBL7590081 0.78 PDE10A (0.58) PDE10ADHODHLMNATSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103385-A Cis-platinum (II) oligomer hybrids 都柏林城市大学 2024-05-28 CN claimed
CN-118103385-A Cis-platinum (II) oligomer hybrids 都柏林城市大学 2024-05-28 CN disclosed
EP-0617288-B1 Long emission wavelength chemiluminescent compounds and their use in test assays NOVARTIS AG (CH) 2002-05-02 EP disclosed
US-5395752-A Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds CIBA CORNING DIAGNOSTICS CORP. (US) 1995-03-07 US disclosed
WO-1994021823-A1 LONG EMISSION WAVELENGTH CHEMILUMINESCENT COMPOUNDS AND THEIR USE IN TEST ASSAYS CIBA CORNING DIAGNOSTICS CORP. (US) 1994-09-29 WO disclosed
EP-0617288-A2 Long emission wavelength chemiluminescent compounds and their use in test assays CIBA-GEIGY AG (CH) 1994-09-28 EP disclosed