Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598947 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8073685 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1HPGDDRD1MEN1 | |
| SCHEMBL9885874 | 0.71 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1POLBMAPTHPGD | |
| SCHEMBL8069213 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1POLBMAPTHPGD | |
| SCHEMBL7037489 | 0.71 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1MAPTHPGDDRD1 | |
| SCHEMBL2107018 | 0.71 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL599846 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1443402 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1POLBHPGDMEN1 | |
| SCHEMBL7031964 | 0.70 | KMT2A (0.39) | SMN1; SMN2ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL1484512 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG IND LTD (KR) | 2002-05-08 | — | — | EP | disclosed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |