SCHEMBL7534153

SCHEMBL7534153

CCCCC(CC)Cc1ccc2cc3ccccc3cc2c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
GLA P06280 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CA2 P00918 1/20 0.40
CYP3A4 P08684 1/20 0.40
TACR3 P29371 1/20 0.39
MMP1 P03956 2/20 0.38
MMP7 P09237 1/20 0.38
ACE P12821 1/20 0.38
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6573171 0.89 ALDH1A1 (0.42) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL18143014 0.84 PRSS1 (0.44) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL2270616 0.81 ALDH1A1 (0.43) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL16143829 0.81 KDM4E (0.47) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL28805342 0.80 ALDH1A1 (0.35) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL4321856 0.79 ALDH1A1 (0.49) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL29023631 0.79 ALDH1A1 (0.38) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL8335252 0.79 ALDH1A1 (0.55) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL161172 0.79 BID (0.55) ALDH1A1KDM4EGLAMEN1KMT2A
SCHEMBL18143012 0.79 PRSS1 (0.43) ALDH1A1KDM4EGLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020085981-A1 BENZOXAZOLE DERIVATIVES FOR USE IN COSMETIC COMPOSITIONS AND FOR STABILIZING SYNTHETIC POLYMERS GE MEDICAL SYSTEMS GLOBAL TECHNOLOGY COMPANY, LLC, A DELAWARE LIMITED LIABILITY COMPANY 2002-07-04 US disclosed
US-6399047-B1 HIGH ULTRAVIOLET RADIATION PROTECTION IN 320 TO 360 NM RANGE; PHOTOSTABILITY; SOLUBLE IN OILY SOLVENTS; TRIPHENYLAMINO-TRIAZINE SUBSTITUENT 3V SIGMA S.P.A. (IT) 2002-06-04 US disclosed
EP-1123934-A1 Benzoxazole derivatives useful as UV filters 3V SIGMA S.p.A (IT) 2001-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020085981-A1 BENZOXAZOLE DERIVATIVES FOR USE IN COSMETIC COMPOSITIONS AND FOR STABILIZING SYNTHETIC POLYMERS CUTA, TYR, PAOX ALDH1A1 605/4885KDM4E 744/4885GLA 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.