SCHEMBL7534282

SCHEMBL7534282

CC(CCCNC=O)c1cccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
ADH1B P00325 2/20 0.35
ADH1C P00326 2/20 0.35
ADH1A P07327 2/20 0.35
ADH7 P40394 2/20 0.35
ALOX5 P09917 1/20 0.35
LMNA P02545 2/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
THRB P10828 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
EPHX1 P07099 1/20 0.34
ADH4 P08319 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706273 0.75 TP53 (0.40) SMN1; SMN2ALOX5LMNATP53POLB
SCHEMBL175346 0.75 GLA (0.40) SMN1; SMN2ALOX5LMNATP53POLB
SCHEMBL5543402 0.74 HTR2A (0.44) ADH1BADH1CADH1AADH7LMNA
SCHEMBL13069188 0.74 SLC6A2 (0.49) KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL22025440 0.74 ALOX5 (0.37) ALOX5LMNATP53POLBTHRB
SCHEMBL24767490 0.74 SLC6A2 (0.49) KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL6002738 0.74 ALOX5 (0.37) SMN1; SMN2ALOX5LMNATP53POLB
SCHEMBL13285005 0.74 SLC6A2 (0.49) KMT2ASLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL19379620 0.73 CACNA2D1 (0.45) TDP1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL4948031 0.72 HDAC1 (0.38) ALOX5LMNANPSR1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1198172-A1 USE OF N-SUBSTITUTED HETEROCYCLYLALKYLAMINES AS HERBICIDES AND NOVEL N-SUBSTITUTED THIENYLALKYLAMINES Bayer Aktiengesellschaft (DE) 2002-04-24 EP disclosed
EP-1087965-A1 THIENYLALKYLAMINO-1,3,5-TRIAZINES AND THE USE THEREOF AS HERBICIDES BAYER AG (DE) 2001-04-04 EP disclosed
WO-2000065916-A1 USE OF N-SUBSTITUTED HETEROCYCLYLALKYLAMINES AS HERBICIDES AND NOVEL N-SUBSTITUTED THIENYLALKYLAMINES BAYER AKTIENGESELLSCHAFT (DE) 2000-11-09 WO disclosed
WO-1999052904-A1 THIENYLALKYLAMINO-1,3,5-TRIAZINES AND THE USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO disclosed