Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciprokiren SCHEMBL564425 | 0.87 | REN (0.61) | REN | |
| SCHEMBL7534571 | 0.87 | REN (0.57) | REN | |
| Ciprokiren SCHEMBL7530263 | 0.87 | REN (0.61) | REN | |
| SCHEMBL8238642 | 0.83 | REN (0.59) | REN | |
| SCHEMBL7436746 | 0.81 | REN (0.55) | REN | |
| SCHEMBL7534258 | 0.81 | REN (0.54) | REN | |
| SCHEMBL7532148 | 0.81 | REN (0.51) | REN | |
| SCHEMBL7344088 | 0.81 | REN (0.62) | REN | |
| SCHEMBL7535138 | 0.81 | REN (0.63) | REN | |
| SCHEMBL7335680 | 0.81 | REN (0.63) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274171-A1 | Renin Inhibitors Nitroderivatives | NICOX S.A. (FR) | 2008-11-06 | — | — | US | disclosed |
| WO-2007045551-A2 | RENIN INHIBITORS NITRODERIVATIVES | NICOX S.A. (FR) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274171-A1 | Renin Inhibitors Nitroderivatives | REN, AGTR1, ACE | REN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.