Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669858 | 0.96 | ALDH1A1 (0.34) | ALDH1A1HSD17B10KDM4EMEN1CYP1A2 | |
| SCHEMBL753503 | 0.87 | KDM4E (0.30) | ALDH1A1HSD17B10KDM4EMEN1CYP1A2 | |
| SCHEMBL13674217 | 0.79 | ALDH1A1 (0.31) | ALDH1A1HSD17B10HIF1ACYP3A4ALOX15 | |
| SCHEMBL753460 | 0.79 | CYP2A6 (0.39) | ALDH1A1HSD17B10CYP1A2HPGDHIF1A | |
| SCHEMBL12873466 | 0.79 | GPR84 (0.35) | ALDH1A1HSD17B10KDM4EMEN1CYP1A2 | |
| SCHEMBL12873463 | 0.78 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL13304280 | 0.77 | GPR84 (0.34) | ALDH1A1HSD17B10KDM4EMEN1CYP1A2 | |
| SCHEMBL18566177 | 0.77 | KDM4E (0.34) | ALDH1A1HSD17B10KDM4EMEN1HPGD | |
| SCHEMBL13304282 | 0.75 | ESR1 (0.36) | ALDH1A1HSD17B10KDM4EMEN1CYP1A2 | |
| SCHEMBL753447 | 0.75 | CYP2A6 (0.42) | ALDH1A1HSD17B10MEN1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138355-B2 | Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same | TOSOH CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138355-B2 | Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same | TOSOH CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |