Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544789 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL9183739 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL7542183 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL9181450 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL7549059 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL9377082 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL9183141 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL7541410 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL7545567 | 1.00 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL31365964 | 0.87 | L3MBTL1 (0.60) | RAB9ASMN1; SMN2NPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882716-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6046201-A | Pyridinecarboxamide derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0882716-A1 | PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0473027-B1 | Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same | NISSHIN FLOUR MILLING CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5250526-A | Hypotensive agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0473027-A1 | Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |