Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857389 | 0.89 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL8857401 | 0.89 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL10879331 | 0.86 | LMNA (0.50) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| SCHEMBL11832490 | 0.80 | LMNA (0.54) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| SCHEMBL621840 | 0.79 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL11694407 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL11023150 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2 | |
| Diatrizoic Acid SCHEMBL8508 | 0.75 | LMNA (0.67) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| Diatrizoic Acid SCHEMBL7615048 | 0.75 | LMNA (0.67) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| SCHEMBL10875389 | 0.74 | LMNA (0.68) | LMNASMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736056-B1 | CASCADE POLYMERS WITH IODINE AROMATIC COMPOUNDS | SCHERING AG (DE) | 2002-05-08 | — | — | EP | disclosed |
| US-5756066-A | Iodine-containing peptides | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0832150-A1 | CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-04-01 | — | — | EP | disclosed |
| US-5593660-A | Cascade polymers with iodoaromatic compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| WO-1996041830-A1 | CASCADE POLYMERS WITH IODINE-CONTAINING AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | WO | disclosed |
| WO-1996040816-A1 | IODINE-CONTAINING LINEAR POLYAMINES AND POLYAMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-19 | — | — | WO | disclosed |
| EP-0736056-A1 | CASCADE POLYMERS WITH IODINE AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017448-A2 | CASCADE POLYMERS WITH IODINE AROMATIC COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |