Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694407 | 0.89 | LMNA (0.40) | LMNASMN1; SMN2DAO | |
| SCHEMBL7534673 | 0.86 | LMNA (0.51) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| SCHEMBL10878087 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL11693012 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL11832490 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2HPGDPTPRBHSD17B10 | |
| SCHEMBL8857401 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL8857389 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2 | |
| Iosarcol SCHEMBL373108 | 0.76 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2 | |
| Iosarcol SCHEMBL29473413 | 0.76 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2 | |
| SCHEMBL8910315 | 0.75 | LMNA (0.43) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607123-A | X-RAY CONTRAST AGENTS | DR. FRANZ KOHLER CHEMIE GMBH (DE) | 1986-08-19 | — | — | US | disclosed |