Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | MGLL | Q99685 | 5/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400698 | 0.83 | PRMT1 (0.63) | — | |
| SCHEMBL756792 | 0.82 | CA1 (0.69) | TGM2PTGS2 | |
| SCHEMBL11526389 | 0.82 | TGM2 (0.62) | TGM2AVPR2GPR27PTGS2FAAH | |
| SCHEMBL7759448 | 0.80 | TGM2 (0.61) | TGM2AVPR2GPR27PTGS2NPC1 | |
| Fluoride SCHEMBL11786861 | 0.80 | TGM2 (0.61) | TGM2AVPR2GPR27PTGS2FAAH | |
| SCHEMBL11154886 | 0.80 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL11786859 | 0.80 | TGM2 (0.61) | TGM2AVPR2GPR27PTGS2FAAH | |
| SCHEMBL9771442 | 0.80 | TGM2 (0.66) | TGM2AVPR2GPR27PTGS2FAAH | |
| SCHEMBL7289377 | 0.79 | PRMT1 (0.74) | TGM2AVPR2GPR27PTGS2NPC1 | |
| SCHEMBL4920494 | 0.79 | PTGS2 (0.73) | AVPR2GPR27PTGS2FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183246-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071527-A1 | TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-11-30 | — | — | WO | disclosed |