Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226602 | 0.92 | MAOB (0.62) | MAOBMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL22071025 | 0.84 | MAOB (0.60) | MAOBRHEBMEN1KMT2ACYP4F2 | |
| SCHEMBL10046165 | 0.81 | MAOB (0.72) | MAOBMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL308991 | 0.81 | MAOB (0.72) | MAOBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL31160636 | 0.81 | MEN1 (0.59) | MAOBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL5042093 | 0.81 | ALOX5 (0.55) | MAOBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL28410872 | 0.78 | NR4A2 (0.64) | MEN1KMT2ATSHRSMN1; SMN2MRGPRX4 | |
| SCHEMBL16886123 | 0.78 | CYP1A2 (0.58) | MAOBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL31183087 | 0.78 | CYP1A2 (0.58) | MAOBMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL31418062 | 0.78 | MAOB (0.64) | MAOBRHEBMEN1KMT2ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |