Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183515 | 0.84 | SLC18A3 (0.69) | DRD2SIGMAR1CARM1PRMT6 | |
| SCHEMBL4576330 | 0.82 | DRD2 (0.70) | DRD2SLC6A4SIGMAR1DRD3DRD1 | |
| SCHEMBL1443672 | 0.82 | QDPR (0.46) | DRD2DRD1DRD5CARM1PRMT6 | |
| SCHEMBL3399715 | 0.82 | DRD2 (1.00) | DRD2SLC6A4SIGMAR1DRD3DRD1 | |
| SCHEMBL27838550 | 0.78 | SLC18A3 (0.41) | DRD2SIGMAR1CARM1PRMT6 | |
| SCHEMBL3614815 | 0.76 | DRD2 (0.46) | DRD2SLC6A4DRD3 | |
| SCHEMBL3602055 | 0.76 | DRD2 (0.46) | DRD2SLC6A4DRD3 | |
| SCHEMBL3610493 | 0.76 | DRD2 (0.46) | DRD2SLC6A4DRD3 | |
| SCHEMBL21118 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3331807 | 0.75 | DRD2 (0.84) | DRD2SLC6A4SIGMAR1DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240142-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. Carlsson Research AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046145-A1 | NEW MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2001-06-28 | — | — | WO | disclosed |