Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 13/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.71 |
| ▸ | CTSV | O60911 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598923 | 0.91 | AKR1C3 (0.78) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL1415572 | 0.89 | AKR1C3 (0.82) | MAPTGFERAKR1C3AKR1C2CTSV | |
| SCHEMBL29747498 | 0.86 | MAPT (1.00) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL7534675 | 0.86 | MAPT (1.00) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL14598926 | 0.84 | AKR1C3 (0.81) | MAPTGFERAKR1C3AKR1C2CTSV | |
| SCHEMBL8773601 | 0.84 | AKR1C3 (0.81) | MAPTGFERAKR1C3AKR1C2CTSV | |
| SCHEMBL9593627 | 0.83 | MEN1 (0.83) | MAPTGFERAKR1C3AKR1C2CTSV | |
| SCHEMBL9595058 | 0.83 | AKR1C3 (1.00) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL355486 | 0.83 | AKR1C3 (0.72) | MAPTAKR1C3AKR1C2CTSVCTSL | |
| SCHEMBL30213377 | 0.83 | AKR1C3 (0.72) | MAPTAKR1C3AKR1C2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| EP-0617288-B1 | Long emission wavelength chemiluminescent compounds and their use in test assays | NOVARTIS AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| US-5879894-A | DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS | CHIRON DIAGNOSTICS CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5395752-A | Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994021823-A1 | LONG EMISSION WAVELENGTH CHEMILUMINESCENT COMPOUNDS AND THEIR USE IN TEST ASSAYS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0617288-A2 | Long emission wavelength chemiluminescent compounds and their use in test assays | CIBA-GEIGY AG (CH) | 1994-09-28 | — | — | EP | disclosed |